diff --git a/sdk/core/azure-core/azure/core/pipeline/transport/_aiohttp.py b/sdk/core/azure-core/azure/core/pipeline/transport/_aiohttp.py
index e32d0d1c0ae..e6189bd6e70 100644
--- a/sdk/core/azure-core/azure/core/pipeline/transport/_aiohttp.py
+++ b/sdk/core/azure-core/azure/core/pipeline/transport/_aiohttp.py
@@ -23,6 +23,7 @@
 # IN THE SOFTWARE.
 #
 # --------------------------------------------------------------------------
+import sys
 from typing import Any, Optional, AsyncIterator as AsyncIteratorType
 from collections.abc import AsyncIterator
 try:
@@ -58,7 +59,6 @@ class AioHttpTransport(AsyncHttpTransport):
     Fully asynchronous implementation using the aiohttp library.
 
     :param session: The client session.
-    :param loop: The event loop.
     :param bool session_owner: Session owner. Defaults True.
 
     :keyword bool use_env_settings: Uses proxy settings from environment. Defaults to True.
@@ -73,6 +73,8 @@ class AioHttpTransport(AsyncHttpTransport):
             :caption: Asynchronous transport with aiohttp.
     """
     def __init__(self, *, session: Optional[aiohttp.ClientSession] = None, loop=None, session_owner=True, **kwargs):
+        if loop and sys.version_info >= (3, 10):
+            raise ValueError("Starting with Python 3.10, asyncio doesn’t support loop as a parameter anymore")
         self._loop = loop
         self._session_owner = session_owner
         self.session = session
diff --git a/sdk/core/azure-core/tests/test_basic_transport.py b/sdk/core/azure-core/tests/test_basic_transport.py
index 5679b6629f4..d08feda5493 100644
--- a/sdk/core/azure-core/tests/test_basic_transport.py
+++ b/sdk/core/azure-core/tests/test_basic_transport.py
@@ -1138,3 +1138,11 @@ def test_conflict_timeout(caplog):
     with pytest.raises(ValueError):
         with Pipeline(transport) as pipeline:
             pipeline.run(request, connection_timeout=(100, 100), read_timeout = 100)
+
+@pytest.mark.skipif(sys.version_info < (3, 10), reason="Loop parameter is deprecated since Python 3.10")
+def test_aiohttp_loop():
+    import asyncio
+    from azure.core.pipeline.transport import AioHttpTransport
+    loop = asyncio._get_running_loop()
+    with pytest.raises(ValueError):
+        transport = AioHttpTransport(loop=loop)