diff --git a/samples/HttpOverridesSample/HttpOverridesSample.csproj b/samples/HttpOverridesSample/HttpOverridesSample.csproj
index 9c8dc46..5caa62c 100644
--- a/samples/HttpOverridesSample/HttpOverridesSample.csproj
+++ b/samples/HttpOverridesSample/HttpOverridesSample.csproj
@@ -15,4 +15,8 @@
     <PackageReference Include="Microsoft.AspNetCore.Server.Kestrel" Version="$(AspNetCoreVersion)" />
   </ItemGroup>
 
+  <ItemGroup>
+    <PackageReference Include="NETStandard.Library.NETFramework" Version="$(NETStandardLibraryNETFrameworkVersion)" />
+  </ItemGroup>
+
 </Project>
diff --git a/samples/ResponseBufferingSample/ResponseBufferingSample.csproj b/samples/ResponseBufferingSample/ResponseBufferingSample.csproj
index f0aa4a4..1678ae4 100644
--- a/samples/ResponseBufferingSample/ResponseBufferingSample.csproj
+++ b/samples/ResponseBufferingSample/ResponseBufferingSample.csproj
@@ -15,4 +15,8 @@
     <PackageReference Include="Microsoft.AspNetCore.Server.Kestrel" Version="$(AspNetCoreVersion)" />
   </ItemGroup>
 
+  <ItemGroup>
+    <PackageReference Include="NETStandard.Library.NETFramework" Version="$(NETStandardLibraryNETFrameworkVersion)" />
+  </ItemGroup>
+
 </Project>
diff --git a/samples/ResponseCompressionSample/ResponseCompressionSample.csproj b/samples/ResponseCompressionSample/ResponseCompressionSample.csproj
index a5792ad..9f5ab99 100644
--- a/samples/ResponseCompressionSample/ResponseCompressionSample.csproj
+++ b/samples/ResponseCompressionSample/ResponseCompressionSample.csproj
@@ -20,4 +20,8 @@
     <PackageReference Include="Microsoft.Extensions.Logging.Console" Version="$(AspNetCoreVersion)" />
   </ItemGroup>
 
+  <ItemGroup>
+    <PackageReference Include="NETStandard.Library.NETFramework" Version="$(NETStandardLibraryNETFrameworkVersion)" />
+  </ItemGroup>
+
 </Project>
diff --git a/samples/RewriteSample/RewriteSample.csproj b/samples/RewriteSample/RewriteSample.csproj
index f9c78e7..416d269 100644
--- a/samples/RewriteSample/RewriteSample.csproj
+++ b/samples/RewriteSample/RewriteSample.csproj
@@ -16,4 +16,8 @@
     <PackageReference Include="Microsoft.AspNetCore.Server.Kestrel.Https" Version="$(AspNetCoreVersion)" />
   </ItemGroup>
 
+  <ItemGroup>
+    <PackageReference Include="NETStandard.Library.NETFramework" Version="$(NETStandardLibraryNETFrameworkVersion)" />
+  </ItemGroup>
+
 </Project>
diff --git a/src/Microsoft.AspNetCore.ResponseCompression/GzipCompressionProvider.cs b/src/Microsoft.AspNetCore.ResponseCompression/GzipCompressionProvider.cs
index b7716f1..e825b37 100644
--- a/src/Microsoft.AspNetCore.ResponseCompression/GzipCompressionProvider.cs
+++ b/src/Microsoft.AspNetCore.ResponseCompression/GzipCompressionProvider.cs
@@ -37,7 +37,13 @@ namespace Microsoft.AspNetCore.ResponseCompression
         {
             get
             {
+#if NET461
+                return false;
+#elif NETSTANDARD2_0
                 return true;
+#else
+#error target frameworks need to be updated
+#endif
             }
         }
 
diff --git a/src/Microsoft.AspNetCore.ResponseCompression/Microsoft.AspNetCore.ResponseCompression.csproj b/src/Microsoft.AspNetCore.ResponseCompression/Microsoft.AspNetCore.ResponseCompression.csproj
index d87066a..261c6cc 100644
--- a/src/Microsoft.AspNetCore.ResponseCompression/Microsoft.AspNetCore.ResponseCompression.csproj
+++ b/src/Microsoft.AspNetCore.ResponseCompression/Microsoft.AspNetCore.ResponseCompression.csproj
@@ -5,7 +5,7 @@
   <PropertyGroup>
     <VersionPrefix>2.0.0</VersionPrefix>
     <Description>ASP.NET Core middleware for HTTP Response compression.</Description>
-    <TargetFramework>netstandard2.0</TargetFramework>
+    <TargetFrameworks>net461;netstandard2.0</TargetFrameworks>
     <GenerateDocumentationFile>true</GenerateDocumentationFile>
     <PackageTags>aspnetcore</PackageTags>
   </PropertyGroup>
diff --git a/test/Microsoft.AspNetCore.ResponseCompression.Tests/ResponseCompressionMiddlewareTest.cs b/test/Microsoft.AspNetCore.ResponseCompression.Tests/ResponseCompressionMiddlewareTest.cs
index 7b77fea..fd9a989 100644
--- a/test/Microsoft.AspNetCore.ResponseCompression.Tests/ResponseCompressionMiddlewareTest.cs
+++ b/test/Microsoft.AspNetCore.ResponseCompression.Tests/ResponseCompressionMiddlewareTest.cs
@@ -505,9 +505,16 @@ namespace Microsoft.AspNetCore.ResponseCompression.Tests
 
             var response = await client.SendAsync(request, HttpCompletionOption.ResponseHeadersRead);
 
+#if NET461 // Flush not supported, compression disabled
+            Assert.NotNull(response.Content.Headers.GetValues(HeaderNames.ContentMD5));
+            Assert.Empty(response.Content.Headers.ContentEncoding);
+#elif NETCOREAPP2_0 // Flush supported, compression enabled
             IEnumerable<string> contentMD5 = null;
             Assert.False(response.Content.Headers.TryGetValues(HeaderNames.ContentMD5, out contentMD5));
             Assert.Single(response.Content.Headers.ContentEncoding, "gzip");
+#else
+#error Target frameworks need to be updated.
+#endif
 
             var body = await response.Content.ReadAsStreamAsync();
 
@@ -563,9 +570,16 @@ namespace Microsoft.AspNetCore.ResponseCompression.Tests
 
             var response = await client.SendAsync(request, HttpCompletionOption.ResponseHeadersRead);
 
+#if NET461 // Flush not supported, compression disabled
+            Assert.NotNull(response.Content.Headers.GetValues(HeaderNames.ContentMD5));
+            Assert.Empty(response.Content.Headers.ContentEncoding);
+#elif NETCOREAPP2_0 // Flush supported, compression enabled
             IEnumerable<string> contentMD5 = null;
             Assert.False(response.Content.Headers.TryGetValues(HeaderNames.ContentMD5, out contentMD5));
             Assert.Single(response.Content.Headers.ContentEncoding, "gzip");
+#else
+#error Target framework needs to be updated
+#endif
 
             var body = await response.Content.ReadAsStreamAsync();