diff --git a/Libraries/Utilities/MessageQueue.js b/Libraries/Utilities/MessageQueue.js
index 2e542b6c40..e9df21105f 100644
--- a/Libraries/Utilities/MessageQueue.js
+++ b/Libraries/Utilities/MessageQueue.js
@@ -192,10 +192,17 @@ class MessageQueue {
     let debug = this._debugInfo[cbID >> 1];
     let module = debug && this._remoteModuleTable[debug[0]];
     let method = debug && this._remoteMethodTable[debug[0]][debug[1]];
-    invariant(
-      callback,
-      `Callback with id ${cbID}: ${module}.${method}() not found`
-    );
+    if (!callback) {
+      let errorMessage = `Callback with id ${cbID}: ${module}.${method}() not found`;
+      if (method) {
+        errorMessage = `The callback ${method}() exists in module ${module}, `
+        + `but only one callback may be registered to a function in a native module.`;
+      }
+      invariant(
+        callback,
+        errorMessage
+      );
+    }
     let profileName = debug ? '<callback for ' + module + '.' + method + '>' : cbID;
     if (callback && SPY_MODE && __DEV__) {
       console.log('N->JS : ' + profileName + '(' + JSON.stringify(args) + ')');