diff --git a/docker/Dockerfile b/docker/Dockerfile
index 2069be4b..469fd76e 100644
--- a/docker/Dockerfile
+++ b/docker/Dockerfile
@@ -135,10 +135,6 @@ RUN \
 
 COPY docker/conf/initial_setup.py /opt/mozdef/envs/mozdef/docker/conf/initial_setup.py
 
-# We have to replace the python virtualenv path until
-# https://github.com/mozilla/MozDef/issues/421 is fixed
-RUN sed -i 's|/opt/mozdef/envs/mozdef/bin/activate|/opt/mozdef/envs/python/bin/activate|g' /opt/mozdef/envs/mozdef/cron/*.sh
-
 RUN chown -R mozdef:mozdef /opt/mozdef/envs/mozdef
 
 # VOLUMES
diff --git a/docker/compose/mozdef_base/Dockerfile b/docker/compose/mozdef_base/Dockerfile
index 55e30676..a9bc69b7 100644
--- a/docker/compose/mozdef_base/Dockerfile
+++ b/docker/compose/mozdef_base/Dockerfile
@@ -51,9 +51,6 @@ USER root
 RUN chown -R mozdef:mozdef /opt/mozdef/envs/mozdef
 
 USER mozdef
-# We have to replace the python virtualenv path until
-# https://github.com/mozilla/MozDef/issues/421 is fixed
-RUN sed -i 's|/opt/mozdef/envs/mozdef/bin/activate|/opt/mozdef/envs/python/bin/activate|g' /opt/mozdef/envs/mozdef/cron/*.sh
 
 RUN mkdir /opt/mozdef/envs/mozdef/data
 
diff --git a/docker/compose/mozdef_cron/Dockerfile b/docker/compose/mozdef_cron/Dockerfile
index 5fdb7037..03180048 100644
--- a/docker/compose/mozdef_cron/Dockerfile
+++ b/docker/compose/mozdef_cron/Dockerfile
@@ -15,10 +15,6 @@ COPY docker/compose/mozdef_cron/files/healthAndStatus.conf /opt/mozdef/envs/mozd
 COPY docker/compose/mozdef_cron/files/healthToMongo.conf /opt/mozdef/envs/mozdef/cron/healthToMongo.conf
 COPY docker/compose/mozdef_cron/files/syncAlertsToMongo.conf /opt/mozdef/envs/mozdef/cron/syncAlertsToMongo.conf
 
-# We have to replace the python virtualenv path until
-# https://github.com/mozilla/MozDef/issues/421 is fixed
-RUN sed -i 's|/opt/mozdef/envs/mozdef/bin/activate|/opt/mozdef/envs/python/bin/activate|g' /opt/mozdef/envs/mozdef/cron/*.sh
-
 RUN chown -R mozdef:mozdef /opt/mozdef/envs/mozdef/cron
 
 USER mozdef