diff --git a/Makefile-docker b/Makefile-docker
index cfc17ca88f..f5360309a1 100644
--- a/Makefile-docker
+++ b/Makefile-docker
@@ -169,7 +169,7 @@ perf-tests: setup-ui-tests
 .PHONY: lint
 lint: ## lint the code
 	black --check src/ tests/
-	flake8 src/ tests/
+	ruff check .
 	NODE_PATH=$(NODE_MODULES) npm exec $(NPM_ARGS) -- prettier --check '**'
 	curlylint src/
 
@@ -235,6 +235,7 @@ watch_js_tests: ## Run+watch the JavaScript test suite (requires compiled/compre
 .PHONY: format
 format: ## Autoformat our codebase.
 	NODE_PATH=$(NODE_MODULES) npm exec $(NPM_ARGS) -- prettier --write '**'
+	ruff check --fix-only .
 	black src/ tests/
 
 .PHONY: help_submake
diff --git a/locale/generate_category_po_files.py b/locale/generate_category_po_files.py
index d9023de720..7d62e0b915 100755
--- a/locale/generate_category_po_files.py
+++ b/locale/generate_category_po_files.py
@@ -76,7 +76,7 @@ def main():
             print('Skipping locale %s, it has no translations :(' % locale)
             continue
 
-        print("Writing %d translations to %s" % (
+        print('Writing %d translations to %s' % (
             len(translations_for_this_locale), fname))
         write_po(fname, translations_for_this_locale)
 
diff --git a/manage.py b/manage.py
index 9fe20678fe..a1e025e6c2 100755
--- a/manage.py
+++ b/manage.py
@@ -3,7 +3,7 @@ import sys
 import os
 
 
-if __name__ == "__main__":
+if __name__ == '__main__':
     os.environ.setdefault('DJANGO_SETTINGS_MODULE', 'settings')
 
     from django.core.management import execute_from_command_line
diff --git a/pyproject.toml b/pyproject.toml
index ef49b4aad4..e1b5005155 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -2,26 +2,38 @@
 line-length = 88
 target-version = ['py310']
 skip-string-normalization = true
-exclude = '''
+extend-exclude = '''
 (
  /(
    docs
-   | node_modules
-   | build*.py
-   | media
-   | storage
-   | logs
-   | site-static
    | static
    | \.git
-   | \.npm
   )/
   | src/.*/migrations/.*\.py
   | src/olympia/translations/tests/testapp/migrations/.*\.py
-  | src/django-babel/.*\.py
 )
 '''
 
+[tool.ruff]
+exclude = [
+    "docs",
+    "static",
+    ".git",
+    "*/migrations/*.py",
+]
+ignore = ["F405", "B004", "B007", "B009", "B010", "B015", "B017", "B018", "B023", "B026", "B028", "B904", "B905"]
+line-length = 88
+select = [
+    "B",
+    "E",
+    "F",
+    "Q",
+    "W",
+]
+
+[tool.ruff.flake8-quotes]
+inline-quotes = "single"
+
 [tool.pytest.ini_options]
 addopts = "-vs --reuse-db --showlocals --tb=short"
 python_files = "test*.py"
diff --git a/requirements/codestyle.txt b/requirements/codestyle.txt
index 07b6e2c008..5e60aea3fb 100644
--- a/requirements/codestyle.txt
+++ b/requirements/codestyle.txt
@@ -1,24 +1,5 @@
 -r system.txt
 
-# flake8 is required by flake8-mutable
-flake8==6.0.0 \
-    --hash=sha256:3833794e27ff64ea4e9cf5d410082a8b97ff1a06c16aa3d2027339cd0f1195c7 \
-    --hash=sha256:c61007e76655af75e6785a931f452915b371dc48f56efd765247c8fe68f2b181
-flake8-mutable==1.2.0 \
-    --hash=sha256:ee9b77111b867d845177bbc289d87d541445ffcc6029a0c5c65865b42b18c6a6 \
-    --hash=sha256:38fd9dadcbcda6550a916197bc40ed76908119dabb37fbcca30873666c31d2d5
-# mccabe is required by flake8
-mccabe==0.7.0 \
-    --hash=sha256:6c2d30ab6be0e4a46919781807b4f0d834ebdd6c6e3dca0bda5a15f863427b6e \
-    --hash=sha256:348e0240c33b60bbdf4e523192ef919f28cb2c3d7d5c7794f74009290f236325
-# pycodestyle is required by flake8
-pycodestyle==2.10.0 \
-    --hash=sha256:347187bdb476329d98f695c213d7295a846d1152ff4fe9bacb8a9590b8ee7053 \
-    --hash=sha256:8a4eaf0d0495c7395bdab3589ac2db602797d76207242c17d470186815706610
-# pyflakes is required by flake8
-pyflakes==3.0.1 \
-    --hash=sha256:ec55bf7fe21fff7f1ad2f7da62363d749e2a470500eab1b555334b67aa1ef8cf \
-    --hash=sha256:ec8b276a6b60bd80defed25add7e439881c19e64850afd9b346283d4165fd0fd
 # attrs is required by curlylint
 attrs==23.1.0 \
     --hash=sha256:1f28b4522cdc2fb4256ac1a020c78acf9cba2c6b461ccd2c126f3aa8e8335d04 \
@@ -70,9 +51,24 @@ mypy-extensions==1.0.0 \
 platformdirs==3.5.0 \
     --hash=sha256:47692bc24c1958e8b0f13dd727307cff1db103fca36399f457da8e05f222fdc4 \
     --hash=sha256:7954a68d0ba23558d753f73437c55f89027cf8f5108c19844d4b82e5af396335    
-flake8-quotes==3.3.2 \
-    --hash=sha256:6e26892b632dacba517bf27219c459a8396dcfac0f5e8204904c5a4ba9b480e1
 tomli==2.0.1 \
     --hash=sha256:939de3e7a6161af0c887ef91b7d41a53e7c5a1ca976325f429cb46ea9bc30ecc \
     --hash=sha256:de526c12914f0c550d15924c62d72abc48d6fe7364aa87328337a31007fe8a4f
-
+ruff==0.0.264 \
+    --hash=sha256:04ec5d75e4bca754cedd20d53e2ba4920d6259e7579abfb2e8e30c3c80e41b17 \
+    --hash=sha256:05ee163a046fc593d150179d23f4af447fb82f3e59cd34e031ea0868c65bb8e8 \
+    --hash=sha256:068a82a29d80848a56e3d9d4308e6e0ca8b2ecdaf5ac342a292545a59b7f2c21 \
+    --hash=sha256:18a29ed37bf8cfe6dce8a2db56c313a64c0804095108753621f3c3321e0c9c5f \
+    --hash=sha256:323ae6c1702b26c96d0fbf939c5959c37e79021f86b70f63634df918bc77f36e \
+    --hash=sha256:3e2c38449548e122f2612843a7c04e22b4fd491656955c57b8cb05df11639ad6 \
+    --hash=sha256:4564e0f245eb515c6ed63988c21e9c40bcfd485cd1ec63bdd790f9a81d301f15 \
+    --hash=sha256:484e395d1984ab9e1e66bd42e7a5192decfee86998d07d36ee50b2fadccc8734 \
+    --hash=sha256:5a8658ebcc37d62f72840cbdf564171c1a2b6831db482b4d917962541a2f4a44 \
+    --hash=sha256:67326fdc9ac0a1b13e229c6e24e8d115863c52cd710faaaaa588851535281d6c \
+    --hash=sha256:71fd865ebacc1083259b3fb7e3eb45235a86e62e21830b8a6b067be0ec54aa2e \
+    --hash=sha256:8fcd4b693ca1374eb7a5796581c90689f884f98f388740d94f0702fd30f8f78f \
+    --hash=sha256:91c6eb4f979b661a2dd850d9ac803842bb7b66d4926de84f09c787af82590f73 \
+    --hash=sha256:cd4f60ffc3eb15802c554a9c8581bf2117c4d3d06fbc57e0ba58f04cb1aaa47f \
+    --hash=sha256:d628de91e2be7a83128526636097d2dd890669a06143f826f6c591d79aeefbc4 \
+    --hash=sha256:d97ba8db0fb601ffe9ee996ebb97c698e427a2fd4514fefbe7b803111354f783 \
+    --hash=sha256:ec2fa192c035b8b68cc2b91049c561cd69543e2b8c4d157d9aa7727320bedcca
diff --git a/setup.cfg b/setup.cfg
deleted file mode 100644
index 8c720e6970..0000000000
--- a/setup.cfg
+++ /dev/null
@@ -1,19 +0,0 @@
-[flake8]
-# E203: https://github.com/psf/black/issues/315
-# W503: https://www.flake8rules.com/rules/W503.html
-ignore = F999,F405,W503,E203
-max-line-length = 88
-exclude =
-    src/olympia/wsgi.py,
-    docs,
-    node_modules,
-    .npm,
-    build*.py
-    media,
-    storage,
-    logs,
-    site-static,
-    static,
-    .git,
-    */migrations/*.py
-    src/django-babel/
diff --git a/src/olympia/addons/tests/test_views.py b/src/olympia/addons/tests/test_views.py
index 54cbe0f2fd..6e8b480309 100644
--- a/src/olympia/addons/tests/test_views.py
+++ b/src/olympia/addons/tests/test_views.py
@@ -5598,7 +5598,9 @@ class TestAddonSearchView(ESTestCase):
         for i in range(0, 10):
             addon_factory()
         self.refresh()
-        query = '남포역립카페추천 ˇjjtat닷컴ˇ ≡제이제이♠♣ 남포역스파 남포역op남포역유흥≡남포역안마남포역오피 ♠♣'
+        query = (
+            '남포역립카페추천 ˇjjtat닷컴ˇ ≡제이제이♠♣ 남포역스파 남포역op남포역유흥≡남포역안마남포역오피 ♠♣'  # noqa: E501
+        )
         data = self.perform_search(self.url, {'q': query})
         # No results, but no 500 either.
         assert data['count'] == 0
diff --git a/src/olympia/lib/crypto/tasks.py b/src/olympia/lib/crypto/tasks.py
index 0008562b3b..91b52b0dd7 100644
--- a/src/olympia/lib/crypto/tasks.py
+++ b/src/olympia/lib/crypto/tasks.py
@@ -42,7 +42,7 @@ Regards,
 The Add-ons Team
 
 ---
-[1] https://extensionworkshop.com/documentation/publish/signing-and-distribution-overview/  # noqa
+[1] https://extensionworkshop.com/documentation/publish/signing-and-distribution-overview/
 [2] https://wiki.mozilla.org/Release_Management/Calendar
 [3] https://www.mozilla.org/firefox/enterprise/
 --
@@ -50,7 +50,7 @@ The Add-ons Team
 You have received this email because you are a registered developer of a
 Firefox add-on. If you do not want to receive these updates regarding your
 add-on, please sign in to addons.mozilla.org and delete your add-on(s).
-"""
+"""  # noqa: E501
 
 version_regex = re.compile(
     r'^(?P<prefix>.*)(?P<version>\.1\-signed)(|\-(?P<number>\d+))$'
diff --git a/src/olympia/reviewers/tests/test_views.py b/src/olympia/reviewers/tests/test_views.py
index 037f62b48f..7dd5889606 100644
--- a/src/olympia/reviewers/tests/test_views.py
+++ b/src/olympia/reviewers/tests/test_views.py
@@ -1812,7 +1812,9 @@ class TestThemeNominatedQueue(QueueTest):
         )
 
     def test_queue_layout(self):
-        self._test_queue_layout('🎨 New', tab_position=0, total_addons=2, total_queues=2)
+        self._test_queue_layout(
+            '🎨 New', tab_position=0, total_addons=2, total_queues=2
+        )  # noqa: E501
 
     def test_static_theme_filtered_out(self):
         self.addons['Nominated Two'].update(type=amo.ADDON_EXTENSION)