diff --git a/testing/marionette/harness/marionette_harness/runner/base.py b/testing/marionette/harness/marionette_harness/runner/base.py
index 6cb6aca093ab..926aa12c35a6 100644
--- a/testing/marionette/harness/marionette_harness/runner/base.py
+++ b/testing/marionette/harness/marionette_harness/runner/base.py
@@ -421,6 +421,13 @@ class BaseMarionetteArguments(ArgumentParser):
             help="Enable python post-mortem debugger when a test fails."
             " Pass in the debugger you want to use, eg pdb or ipdb.",
         )
+        self.add_argument(
+            "--disable-actors",
+            action="store_true",
+            dest="disable_actors",
+            default=False,
+            help="Disable the usage of JSWindowActors in Marionette.",
+        )
         self.add_argument(
             "--enable-fission",
             action="store_true",
@@ -650,8 +657,9 @@ class BaseMarionetteTestRunner(object):
         verbose=0,
         emulator=False,
         headless=False,
-        enable_webrender=False,
+        disable_actors=False,
         enable_fission=False,
+        enable_webrender=False,
         **kwargs
     ):
         self._appName = None
@@ -697,6 +705,14 @@ class BaseMarionetteTestRunner(object):
         self.headless = headless
         self.enable_webrender = enable_webrender
 
+        self.disable_actors = disable_actors
+        if self.disable_actors:
+            self.prefs.update(
+                {
+                    "marionette.actors.enabled": False,
+                }
+            )
+
         self.enable_fission = enable_fission
         if self.enable_fission:
             self.prefs.update(
@@ -1138,6 +1154,7 @@ class BaseMarionetteTestRunner(object):
                     "appname": self.appName,
                     "manage_instance": self.marionette.instance is not None,
                     "headless": self.headless,
+                    "actors": not self.disable_actors,
                     "webrender": self.enable_webrender,
                 }
             )
diff --git a/testing/marionette/harness/marionette_harness/tests/harness_unit/test_marionette_runner.py b/testing/marionette/harness/marionette_harness/tests/harness_unit/test_marionette_runner.py
index 35077dd47d9c..06c3c14448b2 100644
--- a/testing/marionette/harness/marionette_harness/tests/harness_unit/test_marionette_runner.py
+++ b/testing/marionette/harness/marionette_harness/tests/harness_unit/test_marionette_runner.py
@@ -372,9 +372,17 @@ def test_manifest_basic_args(mock_runner, manifest, monkeypatch):
     assert kwargs["exists"] is False
     assert kwargs["disabled"] is True
     assert kwargs["appname"] == "fake_app"
+    assert kwargs["actors"] is True
     assert "mozinfo_key" in kwargs and kwargs["mozinfo_key"] == "mozinfo_val"
 
 
+def test_manifest_actors_disabled(mock_runner, manifest, monkeypatch):
+    kwargs = get_kwargs_passed_to_manifest(
+        mock_runner, manifest, monkeypatch, disable_actors=True
+    )
+    assert kwargs["actors"] is False
+
+
 @pytest.mark.parametrize("test_tags", (None, ["tag", "tag2"]))
 def test_manifest_with_test_tags(mock_runner, manifest, monkeypatch, test_tags):
     kwargs = get_kwargs_passed_to_manifest(
diff --git a/testing/mozharness/scripts/marionette.py b/testing/mozharness/scripts/marionette.py
index 5b051fa6f4ee..500265663ccf 100755
--- a/testing/mozharness/scripts/marionette.py
+++ b/testing/mozharness/scripts/marionette.py
@@ -144,6 +144,15 @@ class MarionetteTest(TestingMixin, MercurialScript, TransferMixin, CodeCoverageM
                     "help": "Permits a software GL implementation (such as LLVMPipe) to use the GL compositor.",  # NOQA: E501
                 },
             ],
+            [
+                ["--disable-actors"],
+                {
+                    "action": "store_true",
+                    "dest": "disable_actors",
+                    "default": False,
+                    "help": "Disable the usage of JSWindowActors in Marionette.",
+                },
+            ],
             [
                 ["--enable-webrender"],
                 {
@@ -338,6 +347,9 @@ class MarionetteTest(TestingMixin, MercurialScript, TransferMixin, CodeCoverageM
         if self.config.get("app_arg"):
             config_fmt_args["app_arg"] = self.config["app_arg"]
 
+        if self.config["disable_actors"]:
+            cmd.append("--disable-actors")
+
         if self.config["enable_webrender"]:
             cmd.append("--enable-webrender")