diff --git a/toolkit/components/pictureinpicture/tests/browser.ini b/toolkit/components/pictureinpicture/tests/browser.ini
index 4866bd4d9534..ddd4b21f70b6 100644
--- a/toolkit/components/pictureinpicture/tests/browser.ini
+++ b/toolkit/components/pictureinpicture/tests/browser.ini
@@ -98,6 +98,8 @@ skip-if = os == "linux" && bits == 64 # Bug 1605565
 [browser_toggleSimple.js]
 skip-if = os == 'linux' # Bug 1546455
 [browser_toggleTransparentOverlay-1.js]
+skip-if =
+  os == 'linux' && bits == 64 && webrender # Bug 1552288
 [browser_toggleTransparentOverlay-2.js]
 skip-if = os == 'linux' && (debug || asan) # Bug 1546930
 [browser_videoSelection.js]