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requirements.txt |
README.md
Normalized Trend Filtering for Biomedical Datasets
Requirements
Install required modules with:
bash
conda create -n NTF python=3.7 numpy=1.18.1 mkl_random=1.1.0
conda activate NTF
pip install -r requirements.txt
Introduction
Associated paper can be found here:
Data
Paper and datasets used for empirical study:
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VanAllen: RNA-seq DATA, RESPONSE, PAPER
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OpenPBTA: DATA, PAPER
Follow data download instructions from OpenPBTA (ver. release-v9-20191105)
RNA-seq data is found in "pbta-gene-expression-kallisto.stranded.rds"
Response is found in "pbta-histologies.tsv"
Notebooks
Notebooks produce the network figures and Tables 1. and 2.
DATASET.ipynb contains analysis for Lasso, MCP, SCAD, Ridge, GraphTF, NTF-Lasso, NTF-MCP, NTF-SCAD, Laplacian Ridge, and Shuffled Experiments
DATASET_LapRidge.ipynb contains analysis for Lasso + Laplacian Ridge, MCP + Laplacian Ridge, SCAD + Laplacian Ridge